Differential Expression of Fas and Fas Ligand in Acute and Chronic Graft-Versus-Host Disease: Up-Regulation of Fas and Fas Ligand Requires CD8 T Cell Activation and IFN-g Production
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Effect of Fas -670 A/G Gene Polymorphism on Corneal Allograft Endothelial Rejection
Background: Human cornea expresses functional Fas-ligand capable of killing Fas+ activated lymphocytes. Fas expression is partly regulated by -670 A/G polymorphism in the promoter region of Fas gene. Objective: The aim of the present study is to determine the association between Fas-670A/G polymorphism and survival of corneal transplantation. Methods: In 276 graft recipients who mainly underwen...
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تاریخ انتشار 1998